Path ID: DB13173_MESH_D009472_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C000621431 | cerliponase alfa | Drug |
| UniProt:O14773 | Tripeptidyl-peptidase 1 | Protein |
| UniProt:P11717 | Cation-independent mannose-6-phosphate receptor | Protein |
| GO:0007041 | lysosomal transport | BiologicalProcess |
| GO:0005764 | lysosome | CellularComponent |
| GO:0034701 | tripeptidase activity | MolecularActivity |
| MESH:C051596 | lipopigments | ChemicalSubstance |
| MESH:D009472 | Late-infantile neuronal ceroid lipofuscinosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cerliponase Alfa | CHEMICALLY SIMILAR TO | Tripeptidyl-Peptidase 1 |
| Tripeptidyl-Peptidase 1 | PARTICIPATES IN | Tripeptidase Activity |
| Tripeptidyl-Peptidase 1 | MOLECULARLY INTERACTS WITH | Cation-Independent Mannose-6-Phosphate Receptor |
| Cation-Independent Mannose-6-Phosphate Receptor | POSITIVELY REGULATES | Lysosomal Transport |
| Lysosomal Transport | OCCURS IN | Lysosome |
| Lysosome | PARTICIPATES IN | Tripeptidase Activity |
| Tripeptidase Activity | DECREASES ABUNDANCE OF | Lipopigments |
| Lipopigments | POSITIVELY CORRELATED WITH | Late-Infantile Neuronal Ceroid Lipofuscinosis |
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