Path ID: DB13166_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C044958 | zofenopril | Drug |
| MESH:C065520 | zofenoprilate | ChemicalSubstance |
| UniProt:P12821 | Angiotensin-converting enzyme | Protein |
| MESH:D000804 | Angiotensin II | ChemicalSubstance |
| MESH:D014661 | vasoconstriction | Disease |
| MESH:D006973 | hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Zofenopril | HAS METABOLITE | Zofenoprilate |
| Zofenoprilate | DECREASES ACTIVITY OF | Angiotensin-Converting Enzyme |
| Angiotensin-Converting Enzyme | INCREASES ABUNDANCE OF | Angiotensin Ii |
| Angiotensin Ii | CAUSES | Vasoconstriction |
| Vasoconstriction | CONTRIBUTES TO | Hypertensive Disorder |
Reference: