Path ID: DB12930_MESH_D003866_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009888 | Opipramol | Drug |
| UniProt:Q99720 | Sigma non-opioid intracellular receptor 1 | Protein |
| GO:0007269 | Neurotransmitter secretion | BiologicalProcess |
| MESH:D003866 | Depressive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Opipramol | INCREASES ACTIVITY OF | Sigma Non-Opioid Intracellular Receptor 1 |
| Sigma Non-Opioid Intracellular Receptor 1 | POSITIVELY REGULATES | Neurotransmitter Secretion |
| Neurotransmitter Secretion | TREATS | Depressive Disorder |
Comment: Higher doses of opipramol are needed for anti-depressant effect.
Reference: