Path ID: DB12872_MESH_D014842_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014841 | vonicog alfa | Drug |
| UniProt:P04275 | von Willebrand factor | Protein |
| UniProt:P00451 | Coagulation factor VIII | Protein |
| UniProt:P02452 | Collagen alpha-1(I) chain | Protein |
| UBERON:0035965 | wall of blood vessel | GrossAnatomicalStructure |
| GO:0007596 | Blood coagulation | BiologicalProcess |
| MESH:D014842 | Von Willebrand disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Vonicog Alfa | CHEMICALLY SIMILAR TO | Von Willebrand Factor |
| Von Willebrand Factor | INCREASES STABILITY OF | Coagulation Factor Viii |
| Coagulation Factor Viii | POSITIVELY REGULATES | Blood Coagulation |
| Vonicog Alfa | INCREASES ACTIVITY OF | Collagen Alpha-1(I) Chain |
| Collagen Alpha-1(I) Chain | LOCATED IN | Wall Of Blood Vessel |
| Wall Of Blood Vessel | LOCATION OF | Blood Coagulation |
| Blood Coagulation | NEGATIVELY CORRELATED WITH | Von Willebrand Disorder |
Reference: