Path ID: DB12865_MESH_D006962_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C583569 | etelcalcetide | Drug |
| UniProt:P41180 | Extracellular calcium-sensing receptor | Protein |
| GO:0055074 | calcium ion homeostasis | BiologicalProcess |
| HP:0002901 | An abnormally decreased calcium concentration in the blood | PhenotypicFeature |
| HP:0003165 | Elevated circulating parathyroid hormone level | PhenotypicFeature |
| MESH:D006962 | Secondary hyperparathyroidism | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Etelcalcetide | INCREASES ACTIVITY OF | Extracellular Calcium-Sensing Receptor |
| Extracellular Calcium-Sensing Receptor | POSITIVELY REGULATES | Calcium Ion Homeostasis |
| Calcium Ion Homeostasis | NEGATIVELY CORRELATED WITH | An Abnormally Decreased Calcium Concentration In The Blood |
| An Abnormally Decreased Calcium Concentration In The Blood | POSITIVELY CORRELATED WITH | Elevated Circulating Parathyroid Hormone Level |
| Elevated Circulating Parathyroid Hormone Level | POSITIVELY CORRELATED WITH | Secondary Hyperparathyroidism |
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