Path ID: DB12834_MESH_D014245_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C016724 | Secnidazole | Drug |
| GO:0000305 | Response to oxygen radical | BiologicalProcess |
| MESH:D004247 | DNA | ChemicalSubstance |
| taxonomy:5722 | Trichomonas vaginalis | OrganismTaxon |
| MESH:D014245 | Infection by Trichomonas | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Secnidazole | POSITIVELY REGULATES | Response To Oxygen Radical |
| Response To Oxygen Radical | DISRUPTS | Dna |
| Dna | IN TAXON | Trichomonas Vaginalis |
| Trichomonas Vaginalis | CAUSES | Infection By Trichomonas |
Comment: Secnidazole is a prodrug converted to an active form via reduction of nitro groups to radical anions in Trichomonas by a ferredoxin-mediated electron transport system.
Reference: