Path ID: DB12710_MESH_D012559_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB12710 | Perazine | Drug |
| UniProt:P14416 | Dopamine D2 receptor | Protein |
| GO:0061527 | Dopamine secretion, neurotransmission | BiologicalProcess |
| MESH:D004298 | Dopamine | ChemicalSubstance |
| UBERON:0000451 | Prefrontal complex | GrossAnatomicalStructure |
| HP:0000708 | Behavioral abnormality | PhenotypicFeature |
| MESH:D012559 | Schizophrenia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Perazine | DECREASES ACTIVITY OF | Dopamine D2 Receptor |
| Dopamine D2 Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| Dopamine | PARTICIPATES IN | Dopamine Secretion, Neurotransmission |
| Dopamine Secretion, Neurotransmission | LOCATED IN | Prefrontal Complex |
| Prefrontal Complex | REGULATES | Behavioral Abnormality |
| Behavioral Abnormality | MANIFESTATION OF | Schizophrenia |
Reference: