Path ID: DB12459_MESH_D002289_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C116963 | belotecan | Drug |
| UniProt:P11387 | DNA topoisomerase 1 | Protein |
| GO:0003677 | DNA binding | MolecularActivity |
| GO:0006260 | DNA replication | BiologicalProcess |
| MESH:D002289 | Non-small cell lung cancer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Belotecan | DECREASES ACTIVITY OF | Dna Topoisomerase 1 |
| Dna Topoisomerase 1 | POSITIVELY REGULATES | Dna Binding |
| Dna Binding | CORRELATED WITH | Dna Replication |
| Dna Replication | POSITIVELY CORRELATED WITH | Non-Small Cell Lung Cancer |
Reference: