Path ID: DB12412_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C534891 | gemigliptin | Drug |
| UniProt:P27487 | Dipeptidyl peptidase 4 | Protein |
| reactome:R-HSA-381771 | Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | Pathway |
| MESH:D052216 | Glucagon-Like Peptide 1 | ChemicalSubstance |
| GO:0030073 | insulin secretion | BiologicalProcess |
| GO:0070091 | glucagon secretion | BiologicalProcess |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Gemigliptin | DECREASES ACTIVITY OF | Dipeptidyl Peptidase 4 |
| Dipeptidyl Peptidase 4 | PARTICIPATES IN | Synthesis, Secretion, And Inactivation Of Glucagon-Like Peptide-1 (Glp-1) |
| Synthesis, Secretion, And Inactivation Of Glucagon-Like Peptide-1 (Glp-1) | DECREASES ABUNDANCE OF | Glucagon-Like Peptide 1 |
| Glucagon-Like Peptide 1 | POSITIVELY REGULATES | Insulin Secretion |
| Glucagon-Like Peptide 1 | NEGATIVELY REGULATES | Glucagon Secretion |
| Insulin Secretion | NEGATIVELY CORRELATED WITH | Diabetes Mellitus, Type 2 |
| Glucagon Secretion | POSITIVELY CORRELATED WITH | Diabetes Mellitus, Type 2 |
Reference: