Path ID: DB12267_MESH_D002289_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C000598580 | brigatinib | Drug |
| UniProt:Q9UM73 | anaplastic lymphoma kinase (ALK) | Protein |
| UniProt:P00533 | Epidermal growth factor receptor | Protein |
| GO:0008283 | proliferation of cells | BiologicalProcess |
| CL:0001063 | tumor cell | Cell |
| MESH:D002289 | Non-small cell lung cancer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Brigatinib | DECREASES ACTIVITY OF | Anaplastic Lymphoma Kinase (Alk) |
| Anaplastic Lymphoma Kinase (Alk) | POSITIVELY REGULATES | Proliferation Of Cells |
| Brigatinib | DECREASES ACTIVITY OF | Epidermal Growth Factor Receptor |
| Epidermal Growth Factor Receptor | POSITIVELY REGULATES | Proliferation Of Cells |
| Proliferation Of Cells | POSITIVELY CORRELATED WITH | Tumor Cell |
| Tumor Cell | POSITIVELY CORRELATED WITH | Non-Small Cell Lung Cancer |
Reference: