Path ID: DB12230_MESH_D000075222_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C018176 | Bunazosin | Drug |
| UniProt:P35348 | Alpha-1A adrenergic receptor | Protein |
| UniProt:P25100 | Alpha-1D adrenergic receptor | Protein |
| GO:0042310 | Vasoconstriction | BiologicalProcess |
| MESH:D000075222 | Essential hypertension | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Bunazosin | DECREASES ACTIVITY OF | Alpha-1A Adrenergic Receptor |
| Bunazosin | DECREASES ACTIVITY OF | Alpha-1D Adrenergic Receptor |
| Alpha-1A Adrenergic Receptor | POSITIVELY REGULATES | Vasoconstriction |
| Alpha-1D Adrenergic Receptor | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | AFFECTS RISK FOR | Essential Hypertension |
Reference: