Path ID: DB12184_MESH_D003865_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C039979 | Gepirone | Disease |
| UniProt:P08908 | 5-hydroxytryptamine receptor 1A | Protein |
| MESH:D012701 | Serotonin | ChemicalSubstance |
| GO:0060096 | Serotonin secretion, neurotransmission | BiologicalProcess |
| MESH:D003865 | Major depressive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Gepirone | INCREASES ACTIVITY OF | 5-Hydroxytryptamine Receptor 1A |
| 5-Hydroxytryptamine Receptor 1A | POSITIVELY CORRELATED WITH | Serotonin |
| Serotonin | POSITIVELY CORRELATED WITH | Serotonin Secretion, Neurotransmission |
| Serotonin Secretion, Neurotransmission | NEGATIVELY CORRELATED WITH | Major Depressive Disorder |
Reference: