Path ID: DB12017_MESH_D001249_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C034364 | ozagrel | Drug |
| UniProt:P24557 | Thromboxane-A synthase | Protein |
| MESH:D013928 | Thromboxane A2 | ChemicalSubstance |
| GO:0042310 | vasoconstriction | BiologicalProcess |
| HP:0025428 | Bronchospasm | PhenotypicFeature |
| MESH:D001249 | Asthma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ozagrel | DECREASES ACTIVITY OF | Thromboxane-A Synthase |
| Thromboxane-A Synthase | INCREASES ABUNDANCE OF | Thromboxane A2 |
| Thromboxane A2 | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | CONTRIBUTES TO | Bronchospasm |
| Bronchospasm | OCCURS IN | Asthma |
Comment: Ozagrel is in phase III trial.
Reference: