Path ID: DB11693_MESH_D014605_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C484071 | voclosporin | Drug |
| UniProt:P63098 | Calcineurin subunit B type 1 | Protein |
| UniProt:O95644 | Nuclear factor of activated T-cells, cytoplasmic 1 | Protein |
| UniProt:P60568 | interleukin 2 | Protein |
| CL:0000084 | T-Cell | Cell |
| MESH:D014605 | Noninfectious Uveitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Voclosporin | DECREASES ACTIVITY OF | Calcineurin Subunit B Type 1 |
| Calcineurin Subunit B Type 1 | INCREASES ABUNDANCE OF | Nuclear Factor Of Activated T-Cells, Cytoplasmic 1 |
| Nuclear Factor Of Activated T-Cells, Cytoplasmic 1 | INCREASES ABUNDANCE OF | Interleukin 2 |
| Interleukin 2 | PRODUCES | T-Cell |
| T-Cell | CAUSES | Noninfectious Uveitis |
Reference: