Path ID: DB11656_MESH_D010437_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C052785 | rebamipide | Drug |
| GO:0019371 | cyclooxygenase pathway | BiologicalProcess |
| UniProt:P01375 | Tumor necrosis factor | Protein |
| GO:0070254 | mucus secretion | BiologicalProcess |
| GO:0008283 | cell population proliferation | BiologicalProcess |
| GO:0001696 | gastric acid secretion | BiologicalProcess |
| GO:0006954 | inflammatory response | BiologicalProcess |
| MESH:D011453 | Prostaglandins | ChemicalSubstance |
| MESH:D005609 | Free Radicals | ChemicalSubstance |
| MESH:D010437 | Peptic ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Rebamipide | POSITIVELY CORRELATED WITH | Cyclooxygenase Pathway |
| Cyclooxygenase Pathway | INCREASES ABUNDANCE OF | Prostaglandins |
| Prostaglandins | POSITIVELY CORRELATED WITH | Mucus Secretion |
| Prostaglandins | POSITIVELY CORRELATED WITH | Cell Population Proliferation |
| Prostaglandins | NEGATIVELY CORRELATED WITH | Gastric Acid Secretion |
| Mucus Secretion | NEGATIVELY CORRELATED WITH | Peptic Ulcer |
| Cell Population Proliferation | NEGATIVELY CORRELATED WITH | Peptic Ulcer |
| Gastric Acid Secretion | POSITIVELY CORRELATED WITH | Peptic Ulcer |
| Rebamipide | NEGATIVELY CORRELATED WITH | Free Radicals |
| Rebamipide | NEGATIVELY CORRELATED WITH | Tumor Necrosis Factor |
| Tumor Necrosis Factor | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Peptic Ulcer |
| Free Radicals | POSITIVELY CORRELATED WITH | Peptic Ulcer |
Reference: