Path ID: DB11614_MESH_D065631_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C103639 | rupatadine | Drug |
| UniProt:P35367 | Histamine H1 receptor | Protein |
| UniProt:P25105 | Platelet-activating factor receptor | Protein |
| GO:0043117 | positive regulation of vascular permeability | BiologicalProcess |
| GO:0043312 | neutrophil degranulation | BiologicalProcess |
| GO:0006954 | inflammatory response | BiologicalProcess |
| MESH:D065631 | Allergic rhinitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Rupatadine | DECREASES ACTIVITY OF | Histamine H1 Receptor |
| Rupatadine | DECREASES ACTIVITY OF | Platelet-Activating Factor Receptor |
| Histamine H1 Receptor | POSITIVELY CORRELATED WITH | Positive Regulation Of Vascular Permeability |
| Platelet-Activating Factor Receptor | POSITIVELY CORRELATED WITH | Neutrophil Degranulation |
| Positive Regulation Of Vascular Permeability | PARTICIPATES IN | Inflammatory Response |
| Neutrophil Degranulation | PARTICIPATES IN | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Allergic Rhinitis |
Reference: