Path ID: DB11611_MESH_D015352_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C575157 | Lifitegrast | Drug |
| UniProt:P20701 | Integrin alpha-L | Protein |
| GO:0042098 | T cell proliferation | BiologicalProcess |
| GO:0042110 | T cell activation | BiologicalProcess |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| MESH:D015352 | Tear film insufficiency | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lifitegrast | DECREASES ACTIVITY OF | Integrin Alpha-L |
| Integrin Alpha-L | POSITIVELY CORRELATED WITH | T Cell Activation |
| Integrin Alpha-L | POSITIVELY CORRELATED WITH | T Cell Proliferation |
| T Cell Activation | POSITIVELY CORRELATED WITH | Inflammatory Response |
| T Cell Proliferation | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Inflammatory Response | OCCURS IN | Tear Film Insufficiency |
Reference: