Path ID: DB11560_MESH_D033461_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C000593471 | Lesinurad | Drug |
| UniProt:Q96S37 | Solute carrier family 22 member 12 | Protein |
| GO:0097744 | Urate salt excretion | BiologicalProcess |
| MESH:D014527 | Uric Acid | ChemicalSubstance |
| UniProt:Q9NSA0 | Solute carrier family 22 member 11 | Protein |
| MESH:D033461 | Hyperuricemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lesinurad | DECREASES ACTIVITY OF | Solute Carrier Family 22 Member 12 |
| Solute Carrier Family 22 Member 12 | NEGATIVELY CORRELATED WITH | Urate Salt Excretion |
| Urate Salt Excretion | DECREASES ACTIVITY OF | Uric Acid |
| Lesinurad | DECREASES ACTIVITY OF | Solute Carrier Family 22 Member 11 |
| Solute Carrier Family 22 Member 11 | NEGATIVELY CORRELATED WITH | Urate Salt Excretion |
| Uric Acid | POSITIVELY CORRELATED WITH | Hyperuricemia |
Reference: