Path ID: DB09564_MESH_D003920_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C571886 | insulin degludec | Drug |
| UniProt:P06213 | Insulin receptor | Protein |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | MolecularActivity |
| reactome:R-HSA-74713 | IRS activation | Pathway |
| GO:0046323 | glucose import | BiologicalProcess |
| MESH:D003920 | Diabetes mellitus | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Insulin Degludec | INCREASES ACTIVITY OF | Insulin Receptor |
| Insulin Receptor | POSITIVELY REGULATES | Transmembrane Receptor Protein Tyrosine Kinase Activity |
| Transmembrane Receptor Protein Tyrosine Kinase Activity | PARTICIPATES IN | Irs Activation |
| Irs Activation | POSITIVELY CORRELATED WITH | Glucose Import |
| Glucose Import | NEGATIVELY CORRELATED WITH | Diabetes Mellitus |
Reference: