Path ID: DB09331_MESH_D009101_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C556306 | daratumumab | Drug |
| UniProt:P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Protein |
| GO:0016049 | cell growth | BiologicalProcess |
| GO:0006915 | apoptotic process | BiologicalProcess |
| GO:0042100 | B cell proliferation | BiologicalProcess |
| MESH:D009101 | Multiple myeloma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Daratumumab | DECREASES ACTIVITY OF | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 |
| Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 | NEGATIVELY REGULATES | Apoptotic Process |
| Apoptotic Process | NEGATIVELY CORRELATED WITH | Multiple Myeloma |
| Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 | POSITIVELY REGULATES | Cell Growth |
| Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 | POSITIVELY REGULATES | B Cell Proliferation |
| Cell Growth | POSITIVELY CORRELATED WITH | Multiple Myeloma |
| B Cell Proliferation | POSITIVELY CORRELATED WITH | Multiple Myeloma |
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