Path ID: DB09304_MESH_D003866_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C050605 | setiptiline | Drug |
| InterPro:IPR002231 | 5-hydroxytryptamine receptor family | GeneFamily |
| GO:0001820 | serotonin secretion | BiologicalProcess |
| GO:0099153 | synaptic transmission, serotonergic | BiologicalProcess |
| MESH:D003866 | Depressive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Setiptiline | DECREASES ACTIVITY OF | 5-Hydroxytryptamine Receptor Family |
| 5-Hydroxytryptamine Receptor Family | NEGATIVELY REGULATES | Serotonin Secretion |
| Serotonin Secretion | PRECEDES | Synaptic Transmission, Serotonergic |
| Synaptic Transmission, Serotonergic | NEGATIVELY CORRELATED WITH | Depressive Disorder |
Reference: