Path ID: DB09303_MESH_D006937_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C577155 | Evolocumab | Drug |
| UniProt:Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | Protein |
| UniProt:P01130 | Low-density lipoprotein receptor | Protein |
| MESH:D008077 | Lipoproteins, LDL | ChemicalSubstance |
| MESH:D006937 | Hypercholesterolemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Evolocumab | DECREASES ACTIVITY OF | Proprotein Convertase Subtilisin/Kexin Type 9 |
| Proprotein Convertase Subtilisin/Kexin Type 9 | DECREASES ACTIVITY OF | Low-Density Lipoprotein Receptor |
| Low-Density Lipoprotein Receptor | DECREASES ABUNDANCE OF | Lipoproteins, Ldl |
| Lipoproteins, Ldl | POSITIVELY CORRELATED WITH | Hypercholesterolemia |
Reference: