Path ID: DB09254_MESH_D003866_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C006919 | caroxazone | Drug |
| UniProt:P27338 | Amine oxidase [flavin-containing] B | Protein |
| UniProt:P21397 | Amine oxidase [flavin-containing] A | Protein |
| GO:0042420 | dopamine catabolic process | BiologicalProcess |
| CHEBI:18243 | dopamine | ChemicalSubstance |
| MESH:D003866 | Depressive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Caroxazone | DECREASES ACTIVITY OF | Amine Oxidase [Flavin-Containing] A |
| Caroxazone | DECREASES ACTIVITY OF | Amine Oxidase [Flavin-Containing] B |
| Amine Oxidase [Flavin-Containing] A | POSITIVELY REGULATES | Dopamine Catabolic Process |
| Amine Oxidase [Flavin-Containing] B | POSITIVELY REGULATES | Dopamine Catabolic Process |
| Dopamine Catabolic Process | DECREASES ABUNDANCE OF | Dopamine |
| Dopamine | NEGATIVELY CORRELATED WITH | Depressive Disorder |
Comment: Withdrawn
Reference: