Path ID: DB09248_MESH_D003866_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C004343 | mebanazine | Drug |
| UniProt:P21397 | Amine oxidase [flavin-containing] A | Protein |
| UniProt:P27338 | Amine oxidase [flavin-containing] B | Protein |
| GO:0042135 | neurotransmitter catabolic process | BiologicalProcess |
| MESH:D003866 | Depressive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Mebanazine | NEGATIVELY REGULATES | Amine Oxidase [Flavin-Containing] A |
| Mebanazine | NEGATIVELY REGULATES | Amine Oxidase [Flavin-Containing] B |
| Amine Oxidase [Flavin-Containing] A | POSITIVELY REGULATES | Neurotransmitter Catabolic Process |
| Amine Oxidase [Flavin-Containing] B | POSITIVELY REGULATES | Neurotransmitter Catabolic Process |
| Neurotransmitter Catabolic Process | POSITIVELY CORRELATED WITH | Depressive Disorder |
Comment: Withdrawn due to hepatotoxicity (https://en.wikipedia.org/wiki/Mebanazine).
Reference: