Path ID: DB09198_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C546215 | lobeglitazone | Drug |
| UniProt:P37231 | Peroxisome proliferator-activated receptor gamma | Protein |
| GO:0032869 | tissue sensitivity to insulin | BiologicalProcess |
| GO:0001951 | uptake of blood glucose | BiologicalProcess |
| MESH:D001786 | glycated hemoglobin | ChemicalSubstance |
| MESH:D003924 | Diabetes mellitus type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lobeglitazone | INCREASES ACTIVITY OF | Peroxisome Proliferator-Activated Receptor Gamma |
| Peroxisome Proliferator-Activated Receptor Gamma | POSITIVELY REGULATES | Tissue Sensitivity To Insulin |
| Tissue Sensitivity To Insulin | INCREASES RESPONSE TO | Uptake Of Blood Glucose |
| Uptake Of Blood Glucose | DECREASES ABUNDANCE OF | Glycated Hemoglobin |
| Glycated Hemoglobin | CORRELATED WITH | Diabetes Mellitus Type 2 |
Reference: