Path ID: DB09108_MESH_D006467_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB09108 | Simoctocog alfa | Drug |
| MESH:D005169 | Factor VIII | ChemicalSubstance |
| UniProt:P00742 | Coagulation factor X | Protein |
| GO:0003809 | Obsolete thrombin activity | BiologicalProcess |
| GO:0072378 | Blood coagulation, fibrin clot formation | BiologicalProcess |
| MESH:D006467 | Hereditary factor VIII deficiency disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Simoctocog Alfa | CHEMICALLY SIMILAR TO | Factor Viii |
| Factor Viii | INCREASES ACTIVITY OF | Coagulation Factor X |
| Coagulation Factor X | POSITIVELY REGULATES | Obsolete Thrombin Activity |
| Obsolete Thrombin Activity | POSITIVELY REGULATES | Blood Coagulation, Fibrin Clot Formation |
| Blood Coagulation, Fibrin Clot Formation | NEGATIVELY CORRELATED WITH | Hereditary Factor Viii Deficiency Disease |
Reference: