Path ID: DB09105_MESH_D007014_1

Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C570710 | asfotase alfa | Drug |
| MESH:C107241 | inorgainc pyrophosphate | ChemicalSubstance |
| GO:0030282 | hydroxpatite crystal growth | BiologicalProcess |
| HP:0004349 | Reduced bone mineral density | PhenotypicFeature |
| MESH:D007014 | Hypophosphatasia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Asfotase Alfa | DECREASES ABUNDANCE OF | Inorgainc Pyrophosphate |
| Inorgainc Pyrophosphate | NEGATIVELY REGULATES | Hydroxpatite Crystal Growth |
| Hydroxpatite Crystal Growth | HAS PHENOTYPE | Reduced Bone Mineral Density |
| Reduced Bone Mineral Density | MANIFESTATION OF | Hypophosphatasia |
Reference: