Path ID: DB09098_MESH_D004393_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C447442 | Somatrem | Drug |
| UniProt:P10912 | Growth hormone receptor | Protein |
| GO:0060396 | Growth hormone receptor signaling pathway | BiologicalProcess |
| UniProt:P05019 | Insulin-like growth factor I | Protein |
| GO:0035264 | Multicellular organism growth | BiologicalProcess |
| MESH:D004393 | Pituitary dwarfism | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Somatrem | INCREASES ACTIVITY OF | Growth Hormone Receptor |
| Growth Hormone Receptor | PARTICIPATES IN | Growth Hormone Receptor Signaling Pathway |
| Growth Hormone Receptor Signaling Pathway | INCREASES ACTIVITY OF | Insulin-Like Growth Factor I |
| Insulin-Like Growth Factor I | POSITIVELY REGULATES | Multicellular Organism Growth |
| Multicellular Organism Growth | NEGATIVELY CORRELATED WITH | Pituitary Dwarfism |
Reference: