Path ID: DB09080_MESH_D029424_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C549647 | olodaterol | Drug |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| GO:0007190 | activation of adenylate cyclase activity | BiologicalProcess |
| MESH:D000242 | Cyclic AMP | ChemicalSubstance |
| GO:0006939 | smooth muscle contraction | BiologicalProcess |
| UBERON:0002185 | bronchus | GrossAnatomicalStructure |
| MESH:D029424 | Pulmonary Disease, Chronic Obstructive | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Olodaterol | INCREASES ACTIVITY OF | Beta-2 Adrenergic Receptor |
| Beta-2 Adrenergic Receptor | POSITIVELY REGULATES | Activation Of Adenylate Cyclase Activity |
| Activation Of Adenylate Cyclase Activity | INCREASES ABUNDANCE OF | Cyclic Amp |
| Cyclic Amp | NEGATIVELY CORRELATED WITH | Smooth Muscle Contraction |
| Smooth Muscle Contraction | OCCURS IN | Bronchus |
| Bronchus | LOCATION OF | Pulmonary Disease, Chronic Obstructive |
Reference: