Path ID: DB09077_MESH_D009447_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB09077 | dinutuximab | Drug |
| CHEBI:28648 | β-D-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1’)-Cer | ChemicalSubstance |
| CL:0001063 | neoplastic cell | Cell |
| GO:0001913 | T cell mediated cytotoxicity | BiologicalProcess |
| GO:0097278 | complement-dependent cytotoxicity | BiologicalProcess |
| MESH:D009447 | Neuroblastoma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dinutuximab | MOLECULARLY INTERACTS WITH | Β-D-Galnac-(1→4)-[Α-Neu5Ac-(2→8)-Α-Neu5Ac-(2→3)]-Β-D-Gal-(1→4)-Β-D-Glc-(1↔1’)-Cer |
| Β-D-Galnac-(1→4)-[Α-Neu5Ac-(2→8)-Α-Neu5Ac-(2→3)]-Β-D-Gal-(1→4)-Β-D-Glc-(1↔1’)-Cer | LOCATED IN | Neoplastic Cell |
| Neoplastic Cell | LOCATION OF | T Cell Mediated Cytotoxicity |
| Neoplastic Cell | LOCATION OF | Complement-Dependent Cytotoxicity |
| T Cell Mediated Cytotoxicity | NEGATIVELY CORRELATED WITH | Neuroblastoma |
| Complement-Dependent Cytotoxicity | NEGATIVELY CORRELATED WITH | Neuroblastoma |
Reference: