Path ID: DB09046_MESH_D052497_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C415771 | Metreleptin | Drug |
| UniProt:P48357 | Leptin receptor | Protein |
| MESH:D020738 | Leptin | ChemicalSubstance |
| UBERON:0001013 | Adipose tissue | GrossAnatomicalStructure |
| MESH:D052497 | Congenital generalized lipodystrophy | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Metreleptin | INCREASES ACTIVITY OF | Leptin Receptor |
| Leptin Receptor | POSITIVELY CORRELATED WITH | Leptin |
| Leptin | PRODUCED BY | Adipose Tissue |
| Adipose Tissue | NEGATIVELY CORRELATED WITH | Congenital Generalized Lipodystrophy |
Reference: