Path ID: DB09040_MESH_D014009_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C431707 | Efinaconazole | Drug |
| PR:000006147 | Lanosterol 14-alpha demethylase | MacromolecularComplex |
| GO:0006696 | Ergosterol biosynthetic process | BiologicalProcess |
| MESH:D004875 | Ergosterol | ChemicalSubstance |
| GO:0042546 | Cell wall biogenesis | BiologicalProcess |
| taxonomy:5551 | Trichophyton rubrum | OrganismTaxon |
| MESH:D014009 | Onychomycosis due to dermatophyte | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Efinaconazole | DECREASES ACTIVITY OF | Lanosterol 14-Alpha Demethylase |
| Lanosterol 14-Alpha Demethylase | POSITIVELY REGULATES | Ergosterol Biosynthetic Process |
| Ergosterol Biosynthetic Process | INCREASES ABUNDANCE OF | Ergosterol |
| Ergosterol | PARTICIPATES IN | Cell Wall Biogenesis |
| Cell Wall Biogenesis | IN TAXON | Trichophyton Rubrum |
| Trichophyton Rubrum | CAUSES | Onychomycosis Due To Dermatophyte |
Reference: