Path ID: DB09033_MESH_D003424_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C543529 | Vedolizumab | Drug |
| UniProt:P13612 | Integrin alpha-4 | Protein |
| UniProt:P26010 | Integrin beta-7 | Protein |
| UniProt:Q13477 | Mucosal addressin cell adhesion molecule 1 | Protein |
| GO:0072676 | Lymphocyte migration | BiologicalProcess |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| MESH:D003424 | Crohn’s disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Vedolizumab | DECREASES ACTIVITY OF | Integrin Alpha-4 |
| Vedolizumab | DECREASES ACTIVITY OF | Integrin Beta-7 |
| Integrin Alpha-4 | POSITIVELY REGULATES | Mucosal Addressin Cell Adhesion Molecule 1 |
| Integrin Beta-7 | POSITIVELY REGULATES | Mucosal Addressin Cell Adhesion Molecule 1 |
| Mucosal Addressin Cell Adhesion Molecule 1 | POSITIVELY REGULATES | Lymphocyte Migration |
| Mucosal Addressin Cell Adhesion Molecule 1 | POSITIVELY REGULATES | Inflammatory Response |
| Lymphocyte Migration | POSITIVELY CORRELATED WITH | Crohn’S Disease |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Crohn’S Disease |
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