Path ID: DB08908_MESH_D020529_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069462 | dimethyl fumarate | Drug |
| UniProt:Q14145 | Kelch-like ECH-associated protein 1 | Protein |
| UniProt:Q16236 | Nrf2 | Protein |
| GO:0006979 | Oxidative Stress | BiologicalProcess |
| MESH:D020529 | Relapsing remitting multiple sclerosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dimethyl Fumarate | DECREASES ACTIVITY OF | Kelch-Like Ech-Associated Protein 1 |
| Kelch-Like Ech-Associated Protein 1 | DECREASES ABUNDANCE OF | Nrf2 |
| Nrf2 | NEGATIVELY REGULATES | Oxidative Stress |
| Oxidative Stress | CORRELATED WITH | Relapsing Remitting Multiple Sclerosis |
Reference: