Path ID: DB08900_MESH_D012778_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB08900 | teduglutide | Drug |
| UniProt:O95838 | Glucagon-like peptide receptor | Protein |
| UBERON:0002439 | myenteric nerve plexus | GrossAnatomicalStructure |
| UBERON:0005304 | submucous nerve plexus | GrossAnatomicalStructure |
| CL:1001516 | intestinal enteroendocrine cell | Cell |
| GO:0050892 | intestinal absorption | BiologicalProcess |
| GO:1990768 | gastric acid secretion | BiologicalProcess |
| GO:0001696 | gastric mucosal blood circulation | BiologicalProcess |
| MESH:D012778 | Short bowel syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Teduglutide | INCREASES ACTIVITY OF | Glucagon-Like Peptide Receptor |
| Glucagon-Like Peptide Receptor | LOCATED IN | Myenteric Nerve Plexus |
| Glucagon-Like Peptide Receptor | LOCATED IN | Submucous Nerve Plexus |
| Glucagon-Like Peptide Receptor | LOCATED IN | Intestinal Enteroendocrine Cell |
| Myenteric Nerve Plexus | POSITIVELY CORRELATED WITH | Intestinal Absorption |
| Submucous Nerve Plexus | POSITIVELY CORRELATED WITH | Intestinal Absorption |
| Intestinal Enteroendocrine Cell | POSITIVELY CORRELATED WITH | Intestinal Absorption |
| Glucagon-Like Peptide Receptor | NEGATIVELY CORRELATED WITH | Gastric Acid Secretion |
| Glucagon-Like Peptide Receptor | POSITIVELY CORRELATED WITH | Gastric Mucosal Blood Circulation |
| Gastric Mucosal Blood Circulation | TREATS | Short Bowel Syndrome |
| Gastric Acid Secretion | TREATS | Short Bowel Syndrome |
| Intestinal Absorption | TREATS | Short Bowel Syndrome |
Reference: