Path ID: DB08883_MESH_D004828_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C551441 | perampanel | Drug |
| UniProt:P42261 | Glutamate receptor 1 | Protein |
| GO:0004971 | AMPA glutamate receptor activity | MolecularActivity |
| GO:0019228 | neuronal action potential | BiologicalProcess |
| GO:0050806 | positive regulation of synaptic transmission | BiologicalProcess |
| MESH:D004828 | Epilepsies, Partial | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Perampanel | DECREASES ACTIVITY OF | Glutamate Receptor 1 |
| Glutamate Receptor 1 | POSITIVELY REGULATES | Ampa Glutamate Receptor Activity |
| Ampa Glutamate Receptor Activity | POSITIVELY CORRELATED WITH | Neuronal Action Potential |
| Neuronal Action Potential | CONTRIBUTES TO | Positive Regulation Of Synaptic Transmission |
| Positive Regulation Of Synaptic Transmission | POSITIVELY CORRELATED WITH | Epilepsies, Partial |
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