Path ID: DB08879_MESH_D008180_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C511911 | belimumab | Drug |
| UniProt:Q9Y275 | Tumor necrosis factor ligand superfamily member 13B | Protein |
| GO:0042100 | B cell proliferation | BiologicalProcess |
| GO:0030183 | B cell differentiation | BiologicalProcess |
| GO:0031296 | B cell costimulation | BiologicalProcess |
| MESH:D008180 | Systemic lupus erythematosus | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Belimumab | DECREASES ACTIVITY OF | Tumor Necrosis Factor Ligand Superfamily Member 13B |
| Tumor Necrosis Factor Ligand Superfamily Member 13B | POSITIVELY REGULATES | B Cell Proliferation |
| Tumor Necrosis Factor Ligand Superfamily Member 13B | POSITIVELY REGULATES | B Cell Costimulation |
| Tumor Necrosis Factor Ligand Superfamily Member 13B | POSITIVELY REGULATES | B Cell Differentiation |
| B Cell Proliferation | OCCURS IN | Systemic Lupus Erythematosus |
| B Cell Costimulation | OCCURS IN | Systemic Lupus Erythematosus |
| B Cell Differentiation | OCCURS IN | Systemic Lupus Erythematosus |
Reference: