Path ID: DB08815_MESH_D001714_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069056 | lurasidone | Drug |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| UniProt:P28223 | 5-hydroxytryptamine receptor 2A | Protein |
| GO:0014046 | dopamine secretion | BiologicalProcess |
| HP:0100754 | Mania | PhenotypicFeature |
| MESH:D001714 | Bipolar affective disorder, current episode depression | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lurasidone | DECREASES ACTIVITY OF | D(2) Dopamine Receptor |
| Lurasidone | DECREASES ACTIVITY OF | 5-Hydroxytryptamine Receptor 2A |
| D(2) Dopamine Receptor | POSITIVELY REGULATES | Dopamine Secretion |
| 5-Hydroxytryptamine Receptor 2A | POSITIVELY REGULATES | Dopamine Secretion |
| Dopamine Secretion | POSITIVELY CORRELATED WITH | Mania |
| Mania | MANIFESTATION OF | Bipolar Affective Disorder, Current Episode Depression |
Reference: