Path ID: DB08808_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002046 | bupranolol | Drug |
| InterPro:cd15058 | beta adrenergic receptors (adenoceptors), member of the class A family of seven-transmembrane G protein-coupled receptors | GeneFamily |
| UBERON:0000013 | sympathetic nervous system | GrossAnatomicalStructure |
| UBERON:0018229 | renin-angiotensin system | GrossAnatomicalStructure |
| HP:0032263 | Increased blood pressure | PhenotypicFeature |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Bupranolol | DECREASES ACTIVITY OF | Beta Adrenergic Receptors (Adenoceptors), Member Of The Class A Family Of Seven-Transmembrane G Protein-Coupled Receptors |
| Beta Adrenergic Receptors (Adenoceptors), Member Of The Class A Family Of Seven-Transmembrane G Protein-Coupled Receptors | POSITIVELY REGULATES | Sympathetic Nervous System |
| Sympathetic Nervous System | POSITIVELY CORRELATED WITH | Renin-Angiotensin System |
| Renin-Angiotensin System | POSITIVELY CORRELATED WITH | Increased Blood Pressure |
| Increased Blood Pressure | POSITIVELY CORRELATED WITH | Hypertensive Disorder |
Reference: