Path ID: DB08797_MESH_D020773_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB08797 | Salicylamide | Drug |
| UniProt:P23219 | Prostaglandin G/H synthase 1 | Protein |
| UniProt:P35354 | Prostaglandin G/H synthase 2 | Protein |
| MESH:D011453 | Prostaglandins | ChemicalSubstance |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| MESH:D020773 | Headache disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Salicylamide | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 1 |
| Salicylamide | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 2 |
| Prostaglandin G/H Synthase 1 | INCREASES ABUNDANCE OF | Prostaglandins |
| Prostaglandin G/H Synthase 2 | INCREASES ABUNDANCE OF | Prostaglandins |
| Prostaglandins | PARTICIPATES IN | Inflammatory Response |
| Inflammatory Response | CONTRIBUTES TO | Headache Disorder |
Comment: Salicylamide belongs to a group of drugs called Non-Steroidal Anti-Inflammatory Drug (NSAIDs) https://link.springer.com/referenceworkentry/10.1007%2F978-3-540-29805-2_2823
Reference: