Path ID: DB06824_MESH_D002292_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014266 | Trientine | Drug |
| MESH:D054856 | G-Quadruplexes | ChemicalSubstance |
| UniProt:O14746 | Telomerase reverse transcriptase | Protein |
| GO:0008283 | cell population proliferation | BiologicalProcess |
| CL:0001063 | neoplastic cell | Cell |
| MESH:D002292 | Carcinoma, Renal Cell | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Trientine | MOLECULARLY INTERACTS WITH | G-Quadruplexes |
| G-Quadruplexes | DECREASES ACTIVITY OF | Telomerase Reverse Transcriptase |
| Telomerase Reverse Transcriptase | POSITIVELY REGULATES | Cell Population Proliferation |
| Cell Population Proliferation | OCCURS IN | Neoplastic Cell |
| Neoplastic Cell | CAUSES | Carcinoma, Renal Cell |
Reference: