Path ID: DB06786_MESH_D016460_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D006206 | halcinonide | Drug |
| UniProt:P04150 | Glucocorticoid receptor | Protein |
| HP:0011123 | Inflammatory abnormality of the skin | PhenotypicFeature |
| HP:0000988 | Skin rash | PhenotypicFeature |
| HP:0000989 | Pruritus | PhenotypicFeature |
| MESH:D016460 | Granuloma annulare | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Halcinonide | POSITIVELY REGULATES | Glucocorticoid Receptor |
| Glucocorticoid Receptor | NEGATIVELY CORRELATED WITH | Inflammatory Abnormality Of The Skin |
| Inflammatory Abnormality Of The Skin | SUPERCLASS OF | Pruritus |
| Inflammatory Abnormality Of The Skin | SUPERCLASS OF | Skin Rash |
| Pruritus | MANIFESTATION OF | Granuloma Annulare |
| Skin Rash | MANIFESTATION OF | Granuloma Annulare |
Reference:
- https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1200845/
- https://en.wikipedia.org/wiki/Halcinonide
- https://pubchem.ncbi.nlm.nih.gov/compound/443943#section=Mechanism-of-Action
- https://en.wikipedia.org/wiki/Corticosteroid#Pharmacology
- https://en.wikipedia.org/wiki/Granuloma#Granuloma_annulare