Path ID: DB06774_MESH_D009437_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002211 | Capsaicin | Drug |
| UniProt:Q8NER1 | Transient receptor potential cation channel subfamily V member 1 | Protein |
| MESH:D013373 | Substance P | ChemicalSubstance |
| GO:0070509 | Calcium ion import | BiologicalProcess |
| GO:0005739 | Mitochondrion | CellularComponent |
| CL:0000198 | Pain receptor cell | Cell |
| MESH:D010146 | Pain | Disease |
| MESH:D009437 | Neuralgia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Capsaicin | INCREASES ACTIVITY OF | Transient Receptor Potential Cation Channel Subfamily V Member 1 |
| Capsaicin | DECREASES ABUNDANCE OF | Substance P |
| Transient Receptor Potential Cation Channel Subfamily V Member 1 | POSITIVELY REGULATES | Calcium Ion Import |
| Substance P | POSITIVELY CORRELATED WITH | Pain |
| Calcium Ion Import | DISRUPTS | Mitochondrion |
| Mitochondrion | LOCATED IN | Pain Receptor Cell |
| Pain Receptor Cell | POSITIVELY REGULATES | Pain |
| Pain | MANIFESTATION OF | Neuralgia |
Reference: