Path ID: DB06736_MESH_D001416_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C056498 | aceclofenac | Drug |
| UniProt:P23219 | Prostaglandin G/H synthase 1 | Protein |
| UniProt:P35354 | Prostaglandin G/H synthase 2 | Protein |
| reactome:R-HSA-2162123 | Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Pathway |
| MESH:D011453 | Prostaglandins | ChemicalSubstance |
| HP:0003326 | Myalgia | PhenotypicFeature |
| UBERON:0004479 | musculature of trunk | GrossAnatomicalStructure |
| MESH:D001416 | Backache | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Aceclofenac | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 1 |
| Aceclofenac | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 2 |
| Prostaglandin G/H Synthase 1 | PARTICIPATES IN | Synthesis Of Prostaglandins (Pg) And Thromboxanes (Tx) |
| Prostaglandin G/H Synthase 2 | PARTICIPATES IN | Synthesis Of Prostaglandins (Pg) And Thromboxanes (Tx) |
| Synthesis Of Prostaglandins (Pg) And Thromboxanes (Tx) | INCREASES ABUNDANCE OF | Prostaglandins |
| Prostaglandins | POSITIVELY CORRELATED WITH | Myalgia |
| Myalgia | LOCATED IN | Musculature Of Trunk |
| Musculature Of Trunk | LOCATION OF | Backache |
Reference: