Path ID: DB06710_MESH_D011628_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D008777 | methyltestosterone | Drug |
| UniProt:P10275 | Androgen receptor | Protein |
| GO:0030518 | intracellular steroid hormone receptor signaling pathway | BiologicalProcess |
| GO:0071394 | cellular response to testosterone stimulus | BiologicalProcess |
| GO:0071391 | cellular response to estrogen stimulus | BiologicalProcess |
| GO:0048808 | male genitalia morphogenesis | BiologicalProcess |
| GO:0048807 | female genitalia morphogenesis | BiologicalProcess |
| MESH:D011628 | Puberty, Delayed | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Methyltestosterone | INCREASES ACTIVITY OF | Androgen Receptor |
| Androgen Receptor | POSITIVELY REGULATES | Intracellular Steroid Hormone Receptor Signaling Pathway |
| Intracellular Steroid Hormone Receptor Signaling Pathway | POSITIVELY CORRELATED WITH | Cellular Response To Testosterone Stimulus |
| Intracellular Steroid Hormone Receptor Signaling Pathway | POSITIVELY CORRELATED WITH | Cellular Response To Estrogen Stimulus |
| Cellular Response To Testosterone Stimulus | POSITIVELY CORRELATED WITH | Male Genitalia Morphogenesis |
| Cellular Response To Estrogen Stimulus | POSITIVELY CORRELATED WITH | Female Genitalia Morphogenesis |
| Male Genitalia Morphogenesis | NEGATIVELY CORRELATED WITH | Puberty, Delayed |
| Female Genitalia Morphogenesis | NEGATIVELY CORRELATED WITH | Puberty, Delayed |
Reference: