Path ID: DB06710_MESH_D005058_1

Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D008777 | methyltestosterone | Drug |
| UniProt:P10275 | Androgen receptor | Protein |
| GO:0060742 | epithelial cell differentiation involved in prostate gland development | BiologicalProcess |
| GO:0048808 | male genitalia morphogenesis | BiologicalProcess |
| GO:0008584 | male gonad development | BiologicalProcess |
| GO:0019102 | male somatic sex determination | BiologicalProcess |
| GO:0007283 | spermatogenesis | BiologicalProcess |
| CHEBI:17347 | testosterone | ChemicalSubstance |
| MESH:D005058 | Eunuchism | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Methyltestosterone | INCREASES ACTIVITY OF | Androgen Receptor |
| Androgen Receptor | POSITIVELY REGULATES | Epithelial Cell Differentiation Involved In Prostate Gland Development |
| Androgen Receptor | POSITIVELY REGULATES | Male Genitalia Morphogenesis |
| Androgen Receptor | POSITIVELY REGULATES | Male Gonad Development |
| Androgen Receptor | POSITIVELY REGULATES | Male Somatic Sex Determination |
| Androgen Receptor | POSITIVELY REGULATES | Spermatogenesis |
| Epithelial Cell Differentiation Involved In Prostate Gland Development | POSITIVELY CORRELATED WITH | Testosterone |
| Male Genitalia Morphogenesis | POSITIVELY CORRELATED WITH | Testosterone |
| Male Gonad Development | POSITIVELY CORRELATED WITH | Testosterone |
| Male Somatic Sex Determination | POSITIVELY CORRELATED WITH | Testosterone |
| Spermatogenesis | POSITIVELY CORRELATED WITH | Testosterone |
| Testosterone | NEGATIVELY CORRELATED WITH | Eunuchism |
Comment: MESH:D005058 is named male hypogonadism in the original file.
Reference: