Path ID: DB06655_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069450 | Liraglutide | Drug |
| UniProt:P43220 | Glucagon-like peptide 1 receptor | Protein |
| MESH:D000242 | Cyclic AMP | ChemicalSubstance |
| GO:0035773 | insulin secretion involved in cellular response to glucose stimulus | BiologicalProcess |
| GO:0070091 | glucagon secretion | BiologicalProcess |
| MESH:D001786 | Blood Glucose | ChemicalSubstance |
| HP:0003074 | Hyperglycemia | PhenotypicFeature |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Liraglutide | INCREASES ACTIVITY OF | Glucagon-Like Peptide 1 Receptor |
| Glucagon-Like Peptide 1 Receptor | INCREASES ABUNDANCE OF | Cyclic Amp |
| Cyclic Amp | POSITIVELY REGULATES | Insulin Secretion Involved In Cellular Response To Glucose Stimulus |
| Insulin Secretion Involved In Cellular Response To Glucose Stimulus | NEGATIVELY REGULATES | Glucagon Secretion |
| Glucagon Secretion | INCREASES ABUNDANCE OF | Blood Glucose |
| Blood Glucose | POSITIVELY CORRELATED WITH | Hyperglycemia |
| Hyperglycemia | MANIFESTATION OF | Diabetes Mellitus, Type 2 |
Reference: