Path ID: DB06650_MESH_D015451_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C527517 | Ofatumumab | Drug |
| GO:0001788 | Antibody-dependent cell-mediated cytotoxicity | BiologicalProcess |
| GO:0097278 | Complement-dependent cytotoxicity | BiologicalProcess |
| GO:0001783 | B cell apoptotic process | BiologicalProcess |
| MESH:D015451 | Chronic lymphoid leukemia, disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ofatumumab | POSITIVELY REGULATES | Antibody-Dependent Cell-Mediated Cytotoxicity |
| Ofatumumab | POSITIVELY REGULATES | Complement-Dependent Cytotoxicity |
| Antibody-Dependent Cell-Mediated Cytotoxicity | PRECEDES | B Cell Apoptotic Process |
| Complement-Dependent Cytotoxicity | PRECEDES | B Cell Apoptotic Process |
| B Cell Apoptotic Process | NEGATIVELY CORRELATED WITH | Chronic Lymphoid Leukemia, Disease |
Reference: