Path ID: DB06643_MESH_D015663_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069448 | denosumab | Drug |
| UniProt:O14788 | Tumor necrosis factor ligand superfamily member 11 | Protein |
| GO:0030316 | osteoclast differentiation | BiologicalProcess |
| GO:0045453 | bone resorption | BiologicalProcess |
| MESH:D015663 | Postmenopausal osteoporosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Denosumab | DISRUPTS | Tumor Necrosis Factor Ligand Superfamily Member 11 |
| Tumor Necrosis Factor Ligand Superfamily Member 11 | POSITIVELY REGULATES | Osteoclast Differentiation |
| Osteoclast Differentiation | POSITIVELY CORRELATED WITH | Bone Resorption |
| Bone Resorption | POSITIVELY CORRELATED WITH | Postmenopausal Osteoporosis |
Reference: