Path ID: DB06590_MESH_D013290_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C515501 | Ceftaroline fosamil | Drug |
| CHEBI:70729 | Ceftaroline | ChemicalSubstance |
| InterPro:IPR001460 | Penicillin-binding protein, transpeptidase | GeneFamily |
| GO:0018104 | Cross-linking of the peptidoglycan | BiologicalProcess |
| GO:0009273 | Peptidoglycan-based cell wall biogenesis | BiologicalProcess |
| GO:0005618 | Cell wall | CellularComponent |
| taxonomy:1314 | Streptococcus pyogenes | OrganismTaxon |
| MESH:D013290 | Streptococcus pyogenes infection | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ceftaroline Fosamil | HAS METABOLITE | Ceftaroline |
| Ceftaroline | DECREASES ACTIVITY OF | Penicillin-Binding Protein, Transpeptidase |
| Penicillin-Binding Protein, Transpeptidase | POSITIVELY REGULATES | Cross-Linking Of The Peptidoglycan |
| Cross-Linking Of The Peptidoglycan | POSITIVELY REGULATES | Peptidoglycan-Based Cell Wall Biogenesis |
| Peptidoglycan-Based Cell Wall Biogenesis | HAS OUTPUT | Cell Wall |
| Cell Wall | OCCURS IN | Streptococcus Pyogenes |
| Streptococcus Pyogenes | CAUSES | Streptococcus Pyogenes Infection |
Reference: